ENZAPROST 50 ML
ENZAPROST 50 ML
Prostaglandin
in injectable solution CEVA
Laboratory
ANIMAL HEALTH
Pharmaceutical form:
Solution for injection (Sol.i.)
Composition: per ml:
Dinoprost (trometamol) 5 mg; benzyl alcohol 16.5 mg.
Pharmacological properties:
Dinoprost (trometamol) has luteolytic activity and causes involution of the corpus luteum in
most mammalian species and the appearance of heat and ovulation in females with
cyclic sexual activity.
The administration of Dinoprost causes abortion or childbirth in the bovine and porcine species.
In addition, it has other activities that vary according to different species such as increase
of blood pressure and bronchial constriction. Dinoprost is also a stimulant of
smooth muscle.
Interactions and incompatibilities:
• Since non-steroidal anti-inflammatories can inhibit the synthesis of
endogenous prostaglandin , the concomitant administration of these compounds with the product can decrease the
luteolytic effects.
• Since oxytocics stimulate the production of prostaglandins, the
concomitant administration of these compounds with the product may exacerbate the luteolytic effects.
ENZAPROST 50 ML Indications and species of destination:
Cattle:
• Synchronization of estrus.
• Treatment of silent estrus in cows with a functional corpus luteum but that do not manifest the
heat behavior.
• Induction of abortion until day 120 of gestation.
• Induction of labor.
• Coadjuvant treatment in chronic metritis and pyometra when there is a functional or
persistent corpus luteum .
Porcine:
• Induction of labor as of day 111 of gestation.
• Postpartum use: reduction of weaning intervals (IDC) and weaning fertile cover (IDCF) of
sows with problems in the puerperium, such as metritis in farms with reproductive problems.
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